A novel protein kinase is essential in bloodstream Trypanosoma brucei

Human African trypanosomiasis a fatal disease for which no vaccines exist and treatment regimens are difficult. Here, we evaluate a Trypanosoma brucei protein kinase, AEK1, as a potential drug target. Conditional knockouts confirmed AEK1 essentiality in bloodstream forms. For chemical validation, we...

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Detaylı Bibliyografya
Yayımlandı:Int J Parasitol
Asıl Yazarlar: Jensen, Bryan C., Booster, Nick, Vidadala, Rama Subba Rao, Maly, Dustin J., Parsons, Marilyn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925258/
https://ncbi.nlm.nih.gov/pubmed/27018127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2016.03.001
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