Co-operative binding assay for the characterization of mGlu(4) allosteric modulators

Por Poutiainen, Pekka, Kil, Kun-Eek, Zhang, Zhaoda, Kuruppu, Darshini, Tannous, Bakhos, Brownell, Anna-Liisa
Publicado no Neuropharmacology (2015)

PET imaging studies show enhanced expression of mGluR5 and inflammatory response during progressive degeneration in ALS mouse model expressing SOD1-G93A gene

Por Brownell, Anna-Liisa, Kuruppu, Darshini, Kil, Kun-Eek, Jokivarsi, Kimmo, Poutiainen, Pekka, Zhu, Aijun, Maxwell, Michelle
Publicado no J Neuroinflammation (2015)

Radiosynthesis of N-(4-chloro-3-[(11)C]methoxyphenyl)-2-picolinamide ([(11)C]ML128) as a PET radiotracer for metabotropic glutamate receptor subtype 4 (mGlu(4))

Por Kil, Kun-Eek, Zhang, Zhaoda, Jokivarsi, Kimmo, Gong, Chunyu, Choi, Ji-Kyung, Kura, Sreekanth, Brownell, Anna-Liisa
Publicado em 2013

Development of [(123)I]IPEB and [(123)I]IMPEB as SPECT Radioligands for Metabotropic Glutamate Receptor Subtype 5

Por Kil, Kun-Eek, Zhu, Aijun, Zhang, Zhaoda, Choi, Ji-Kyung, Kura, Sreekanth, Gong, Chunyu, Brownell, Anna-Liisa
Publicado em 2014

Radiosynthesis and Evaluation of an (18)F-Labeled Positron Emission Tomography (PET) Radioligand for Metabotropic Glutamate Receptor Subtype 4 (mGlu(4))

Por Kil, Kun-Eek, Poutiainen, Pekka, Zhang, Zhaoda, Zhu, Aijun, Choi, Ji-Kyung, Jokivarsi, Kimmo, Brownell, Anna-Liisa
Publicado no J Med Chem (2014)

Hypo-anxious phenotype of adolescent offspring prenatally exposed to LPS is associated with reduced mGluR5 expression in hippocampus

Por Arsenault, Dany, Zhu, Aijun, Gong, Chunyu, Kil, Kun-Eek, Kura, Sreekanth, Choi, Ji-Kyung, Brownell, Anna-Liisa
Publicado no Open J Med Psychol (2014)

Loss of Metabotropic Glutamate Receptor 5 Function on Peripheral Benzodiazepine Receptor in Mice Prenatally Exposed to LPS

Por Arsenault, Dany, Coulombe, Katherine, Zhu, Aijun, Gong, Chunyu, Kil, Kun-Eek, Choi, Ji-Kyung, Poutiainen, Pekka, Brownell, Anna-Liisa
Publicado no PLoS One (2015)

Synthesis and positron emission tomography studies of carbon-11-labeled imatinib (Gleevec)

Por Kil, Kun-Eek, Ding, Yu-Shin, Lin, Kuo-Shyan, Alexoff, David, Kim, Sung Won, Shea, Colleen, Xu, Youwen, Muench, Lisa, Fowler, Joanna S.
Publicado em 2007

Re-exploring the N-phenylpicolinamide derivatives to develop mGlu(4) ligands with improved affinity and in vitro microsomal stability

Por Zhang, Zhaoda, Kil, Kun-Eek, Poutiainen, Pekka, Choi, Ji-Kyung, Kang, Hye-Jin, Huang, Xi-Ping, Roth, Bryan L, Brownell, Anna-Liisa
Publicado no Bioorg Med Chem Lett (2015)

Synthesis and evaluation of N-(methylthiophenyl)picolinamide derivatives as PET radioligands for metabotropic glutamate receptor subtype 4

Por Kil, Kun-Eek, Poutiainen, Pekka, Zhang, Zhaoda, Zhu, Aijun, Kuruppu, Darshini, Prabhakar, Shilpa, Choi, Ji-Kyung, Tannous, Bakhos A., Brownell, Anna-Liisa
Publicado no Bioorg Med Chem Lett (2015)

Synthesis and PET studies of [(11)C-cyano]letrozole (Femara(®)), an aromatase inhibitor drug

Por Kil, Kun-Eek, Biegon, Anat, Ding, Yu-Shin, Fischer, Andre, Ferrieri, Richard A., Kim, Sung Won, Pareto, Deborah, Schueller, Michael J., Fowler, Joanna S.
Publicado em 2009

Functional modulation of G-protein coupled receptors during Parkinson disease-like neurodegeneration

Por Jenkins, Bruce, Zhu, Aijun, Poutiainen, Pekka, Choi, Ji-Kyung, Kil, Kun-Eek, Zhang, Zhaoda, Kuruppu, Darshini, Aytan, Nurgul, Dedeoglu, Alpaslan, Brownell, Anna-Liisa
Publicado no Neuropharmacology (2015)

Synthesis, radiolabeling and initial in vivo evaluation of [(11)C]KSM-01 for imaging PPAR-α receptors

Por Solingapuram Sai, Kiran Kumar, Kil, Kun-eek, Tu, Zhude, Chu, Wenhua, Finck, Brian N., Rothfuss, Justin M., Shoghi, Kooresh I., Welch, Michael J., Gropler, Robert J., Mach, Robert H.
Publicado em 2012