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Re-exploring the N-phenylpicolinamide derivatives to develop mGlu(4) ligands with improved affinity and in vitro microsomal stability
In recent years, mGlu(4) has received great attention and research effort because of the potential benefits of mGlu(4) activation in treating numerous brain disorders, such as Parkinson’s disease (PD). Many positive allosteric modulators of mGlu(4) have been developed. To better understand the role...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539532/ https://ncbi.nlm.nih.gov/pubmed/26231155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.07.031 |
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