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Synthesis and evaluation of N-(methylthiophenyl)picolinamide derivatives as PET radioligands for metabotropic glutamate receptor subtype 4
In recent years, mGlu(4) has received great research attention because of the potential benefits of mGlu(4) activation in treating numerous brain disorders, such as Parkinson’s disease (PD). A specific mGlu(4) PET radioligand could be an important tool in understanding the role of mGlu(4) in both he...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684791/ https://ncbi.nlm.nih.gov/pubmed/26602273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.11.015 |
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