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Development of [(123)I]IPEB and [(123)I]IMPEB as SPECT Radioligands for Metabotropic Glutamate Receptor Subtype 5

[Image: see text] mGlu(5) play an important role in physiology and pathology to various central nervous system (CNS) diseases. Several positron emission tomography (PET) radiotracers have been developed to explore the role of mGlu(5) in brain disorders. However, there are no single photon emission c...

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Detalhes bibliográficos
Main Authors: Kil, Kun-Eek, Zhu, Aijun, Zhang, Zhaoda, Choi, Ji-Kyung, Kura, Sreekanth, Gong, Chunyu, Brownell, Anna-Liisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060925/
https://ncbi.nlm.nih.gov/pubmed/24944738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500007z
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