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Co-operative binding assay for the characterization of mGlu(4) allosteric modulators
The interest in the role of metabotropic glutamate receptor 4 (mGlu(4)) in CNS related disorders has increased the need for methods to investigate the binding of allosteric drug candidates. Our aim is to present the first fully characterized in vitro binding assay of mGlu(4) positive allosteric modu...
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| Publicado no: | Neuropharmacology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4537392/ https://ncbi.nlm.nih.gov/pubmed/26025660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.05.017 |
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