Laddar...

Co-operative binding assay for the characterization of mGlu(4) allosteric modulators

The interest in the role of metabotropic glutamate receptor 4 (mGlu(4)) in CNS related disorders has increased the need for methods to investigate the binding of allosteric drug candidates. Our aim is to present the first fully characterized in vitro binding assay of mGlu(4) positive allosteric modu...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Neuropharmacology
Huvudupphovsmän: Poutiainen, Pekka, Kil, Kun-Eek, Zhang, Zhaoda, Kuruppu, Darshini, Tannous, Bakhos, Brownell, Anna-Liisa
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537392/
https://ncbi.nlm.nih.gov/pubmed/26025660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.05.017
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!