PET imaging studies show enhanced expression of mGluR5 and inflammatory response during progressive degeneration in ALS mouse model expressing SOD1-G93A gene

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative motor neuron disorder. Genetic studies have linked mutation of the gene SOD1 to ALS pathology as well as several other pathological processes including modulation of glutamatergic function and inflammatory processes....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Brownell, Anna-Liisa, Kuruppu, Darshini, Kil, Kun-Eek, Jokivarsi, Kimmo, Poutiainen, Pekka, Zhu, Aijun, Maxwell, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657381/
https://ncbi.nlm.nih.gov/pubmed/26597638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0439-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados