Activity and Mechanism of Action of N-Methanocarbathymidine against Herpesvirus and Orthopoxvirus Infections

מאת Prichard, Mark N., Keith, Kathy A., Quenelle, Debra C., Kern, Earl R.
יצא לאור 2006

Evaluation of Nucleoside Phosphonates and Their Analogs and Prodrugs for Inhibition of Orthopoxvirus Replication

מאת Keith, Kathy A., Hitchcock, Michael J. M., Lee, William A., Holý, Antonin, Kern, Earl R.
יצא לאור 2003

5-(Dimethoxymethyl)-2′-Deoxyuridine: A Novel Gem Diether Nucleoside with Anti-Orthopoxvirus Activity

מאת Fan, Xuesen, Zhang, Xinying, Zhou, Longhu, Keith, Kathy A., Kern, Earl R., Torrence, Paul F.
הוצא לאור ב J Med Chem (2006)

Enhanced Inhibition of Orthopoxvirus Replication In Vitro by Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir

מאת Kern, Earl R., Hartline, Caroll, Harden, Emma, Keith, Kathy, Rodriguez, Natalie, Beadle, James R., Hostetler, Karl Y.
יצא לאור 2002

Inhibitory Activity of Alkoxyalkyl and Alkyl Esters of Cidofovir and Cyclic Cidofovir against Orthopoxvirus Replication In Vitro

מאת Keith, Kathy A., Wan, William B., Ciesla, Stephanie L., Beadle, James R., Hostetler, Karl Y., Kern, Earl R.
יצא לאור 2004

Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine

מאת Prichard, Mark N, Kern, Earl R, Quenelle, Debra C, Keith, Kathy A, Moyer, Richard W, Turner, Peter C
יצא לאור 2008

Toward Orthopoxvirus Countermeasures: A Novel Heteromorphic Nucleoside of Unusual Structure

מאת Fan, Xuesen, Zhang, Xinying, Zhou, Longhu, Keith, Kathy A., Prichard, Mark N., Kern, Earl R., Torrence, Paul F.
הוצא לאור ב J Med Chem (2006)

Efficacy of Delayed Treatment with ST-246 Given Orally against Systemic Orthopoxvirus Infections in Mice

מאת Quenelle, Debra C., Buller, R. M. L., Parker, Scott, Keith, Kathy A., Hruby, Dennis E., Jordan, Robert, Kern, Earl R.
יצא לאור 2007

Synthesis and Antiviral Evaluation of Alkoxyalkyl Phosphate Conjugates of Cidofovir and Adefovir

מאת Ruiz, Jacqueline C., Beadle, James R., Aldern, Kathy A., Keith, Kathy A., Hartline, Caroll B., Kern, Earl R., Hostetler, Karl Y.
יצא לאור 2006

Activities of Certain 5-Substituted 4′-Thiopyrimidine Nucleosides against Orthopoxvirus Infections

מאת Kern, Earl R., Prichard, Mark N., Quenelle, Debra C., Keith, Kathy A., Tiwari, Kamal N., Maddry, Joseph A., Secrist, John A.
יצא לאור 2009

Identification of Protein-Protein Interaction Inhibitors Targeting Vaccinia Virus Processivity Factor for Development of Antiviral Agents

מאת Schormann, Norbert, Sommers, Charnell Inglis, Prichard, Mark N., Keith, Kathy A., Noah, James W., Nuth, Manunya, Ricciardi, Robert P., Chattopadhyay, Debasish
יצא לאור 2011

Synergistic Efficacy of the Combination of ST-246 with CMX001 against Orthopoxviruses

מאת Quenelle, Debra C., Prichard, Mark N., Keith, Kathy A., Hruby, Dennis E., Jordan, Robert, Painter, George R., Robertson, Alice, Kern, Earl R.
יצא לאור 2007

Isolation and characterization of cidofovir resistant vaccinia viruses

מאת Becker, Marie N, Obraztsova, Maria, Kern, Earl R, Quenelle, Debra C, Keith, Kathy A, Prichard, Mark N, Luo, Ming, Moyer, Richard W
יצא לאור 2008

SYNTHESIS, METABOLIC STABILITY AND ANTIVIRAL EVALUATION OF VARIOUS ALKOXYALKYL ESTERS OF CIDOFOVIR AND (S)-[3-HYDROXY-2-(PHOSPHONOMETHOXY)PROPYL]ADENINE

מאת Ruiz, Jacqueline, Beadle, James R., Buller, R. Mark, Schreiwer, Jill, Prichard, Mark N., Keith, Kathy A., Lewis, Kenneth C., Hostetler, Karl Y.
יצא לאור 2011

Effect of Oral Treatment with Hexadecyloxypropyl-[(S)-9-(3-Hydroxy-2- Phosphonylmethoxypropyl)Adenine] [(S)-HPMPA] or Octadecyloxyethyl-(S)-HPMPA on Cowpox or Vaccinia Virus Infect...

מאת Quenelle, Debra C., Collins, Deborah J., Herrod, Bridgett P., Keith, Kathy A., Trahan, Julissa, Beadle, James R., Hostetler, Karl Y., Kern, Earl R.
יצא לאור 2007

Antiviral Evaluation of Octadecyloxyethyl Esters of (S)-3-Hydroxy-2-(phosphonomethoxy)propyl Nucleosides Against Herpesviruses and Orthopoxviruses

מאת Valiaeva, Nadejda, Prichard, Mark N., Buller, R. Mark, Beadle, James R., Hartline, Caroll B., Keith, Kathy A., Schriewer, Jill, Trahan, Julissa, Hostetler, Karl Y.
יצא לאור 2009

Antiviral Activities of Novel 5-Phosphono-Pent-2-en-1-yl Nucleosides and Their Alkoxyalkyl Phosphonoesters

מאת Choo, Hyunah, Beadle, James R., Kern, Earl R., Prichard, Mark N., Keith, Kathy A., Hartline, Caroll B., Trahan, Julissa, Aldern, Kathy A., Korba, Brent E., Hostetler, Karl Y.
יצא לאור 2007

Selective Phosphorylation of Antiviral Drugs by Vaccinia Virus Thymidine Kinase

מאת Prichard, Mark N., Keith, Kathy A., Johnson, Mary P., Harden, Emma A., McBrayer, Alexis, Luo, Ming, Qiu, Shihong, Chattopadhyay, Debasish, Fan, Xuesen, Torrence, Paul F., Kern, Earl R.
יצא לאור 2007

Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides

מאת Williams, John D., Khan, Atiyya R., Harden, Emma A., Hartline, Caroll B., Jefferson, Geraldine M., Keith, Kathy A., Prichard, Mark N., Zemlicka, Jiri, Peet, Norton P., Bowlin, Terry L.
יצא לאור 2012

New Small Molecule Entry Inhibitors Targeting Hemagglutinin-Mediated Influenza A Virus Fusion

מאת Basu, Arnab, Antanasijevic, Aleksandar, Wang, Minxiu, Li, Bing, Mills, Debra M., Ames, Jessica A., Nash, Peter J., Williams, John D., Peet, Norton P., Moir, Donald T., Prichard, Mark N., Keith, Kathy A., Barnard, Dale L., Caffrey, Michael, Rong, Lijun, Bowlin, Terry L.
יצא לאור 2014