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Synergistic Efficacy of the Combination of ST-246 with CMX001 against Orthopoxviruses

The combination of ST-246 and hexadecyloxypropyl-cidofovir or CMX001 was evaluated for synergistic activity in vitro against vaccinia virus and cowpox virus (CV) and in vivo against CV. In cell culture the combination was highly synergistic against both viruses, and the results suggested that combin...

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Detalhes bibliográficos
Main Authors: Quenelle, Debra C., Prichard, Mark N., Keith, Kathy A., Hruby, Dennis E., Jordan, Robert, Painter, George R., Robertson, Alice, Kern, Earl R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151443/
https://ncbi.nlm.nih.gov/pubmed/17724153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00762-07
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