Enhanced Inhibition of Orthopoxvirus Replication In Vitro by Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir

The nucleotide phosphonates cidofovir (CDV) and cyclic cidofovir (cCDV) are potent antiviral compounds when administered parenterally but are not well absorbed orally. These compounds have been reported to have activity against orthopoxvirus replication in vitro and in animal models when administere...

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Autors principals: Kern, Earl R., Hartline, Caroll, Harden, Emma, Keith, Kathy, Rodriguez, Natalie, Beadle, James R., Hostetler, Karl Y.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC127114/
https://ncbi.nlm.nih.gov/pubmed/11897580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.4.991-995.2002
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