Selective Phosphorylation of Antiviral Drugs by Vaccinia Virus Thymidine Kinase

The antiviral activity of a new series of thymidine analogs was determined against vaccinia virus (VV), cowpox virus (CV), herpes simplex virus, and varicella-zoster virus. Several compounds were identified that had good activity against each of the viruses, including a set of novel 5-substituted de...

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Main Authors: Prichard, Mark N., Keith, Kathy A., Johnson, Mary P., Harden, Emma A., McBrayer, Alexis, Luo, Ming, Qiu, Shihong, Chattopadhyay, Debasish, Fan, Xuesen, Torrence, Paul F., Kern, Earl R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855528/
https://ncbi.nlm.nih.gov/pubmed/17325220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01447-06
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