Antiviral Activities of Novel 5-Phosphono-Pent-2-en-1-yl Nucleosides and Their Alkoxyalkyl Phosphonoesters

Three acyclic nucleoside phosphonates are currently approved for clinical use against infections caused by cytomegalovirus (Vistide), hepatitis B virus (Hepsera), and human immunodeficiency virus type 1 (Viread). This important antiviral class inhibits viral polymerases after cellular uptake and con...

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Bibliografski detalji
Glavni autori: Choo, Hyunah, Beadle, James R., Kern, Earl R., Prichard, Mark N., Keith, Kathy A., Hartline, Caroll B., Trahan, Julissa, Aldern, Kathy A., Korba, Brent E., Hostetler, Karl Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Antiviral Agents
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797766/
https://ncbi.nlm.nih.gov/pubmed/17130297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00444-06
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