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Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides
A second-generation series of substituted methylenecyclopropane nucleosides (MCPNs) has been synthesized and evaluated for antiviral activity against a panel of human herpesviruses, and for cytotoxicity. Although alkylated 2,6-diaminopurine analogs showed little antiviral activity, the compounds con...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509806/ https://ncbi.nlm.nih.gov/pubmed/22607883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.04.049 |
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