Synthesis and Antiviral Activities of Methylenecyclopropane Analogs with 6-Alkoxy and 6-Alkylthio Substitutions That Exhibit Broad-Spectrum Antiviral Activity against Human Herpesviruses

Methylenecyclopropane nucleosides have been reported to be active against many of the human herpesviruses. The most active compound of this class is cyclopropavir (CPV), which exhibits good antiviral activity against human cytomegalovirus (HCMV), Epstein-Barr virus, both variants of human herpesviru...

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Detalhes bibliográficos
Principais autores: Prichard, Mark N., Williams, John D., Komazin-Meredith, Gloria, Khan, Atiyya R., Price, Nathan B., Jefferson, Geraldine M., Harden, Emma A., Hartline, Caroll B., Peet, Norton P., Bowlin, Terry L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719742/
https://ncbi.nlm.nih.gov/pubmed/23669381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00429-13
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