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Activities of Certain 5-Substituted 4′-Thiopyrimidine Nucleosides against Orthopoxvirus Infections

As part of a program to identify new compounds that have activity against orthopoxviruses, a number of 4′-thionucleosides were synthesized and evaluated for their efficacies against vaccinia and cowpox viruses. Seven compounds that were active at about 1 μM against both viruses in human cells but th...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Kern, Earl R., Prichard, Mark N., Quenelle, Debra C., Keith, Kathy A., Tiwari, Kamal N., Maddry, Joseph A., Secrist, John A.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology (ASM) 2009
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630668/
https://ncbi.nlm.nih.gov/pubmed/19029322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01257-08
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