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5-(Dimethoxymethyl)-2′-Deoxyuridine: A Novel Gem Diether Nucleoside with Anti-Orthopoxvirus Activity
To provide potential new leads for the treatment of orthopoxvirus infections, the 5-position of the pyrimidine nucleosides have been modified with a gem diether moiety to yield the following new nucleosides: 5-(dimethoxymethyl)-2′-deoxyuridine (2b), 5-(diethoxymethyl)-2′-deoxyuridine (3b), 5-formyl-...
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| Publicat a: | J Med Chem |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262926/ https://ncbi.nlm.nih.gov/pubmed/16722657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0601710 |
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