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5-(Dimethoxymethyl)-2′-Deoxyuridine: A Novel Gem Diether Nucleoside with Anti-Orthopoxvirus Activity
To provide potential new leads for the treatment of orthopoxvirus infections, the 5-position of the pyrimidine nucleosides have been modified with a gem diether moiety to yield the following new nucleosides: 5-(dimethoxymethyl)-2′-deoxyuridine (2b), 5-(diethoxymethyl)-2′-deoxyuridine (3b), 5-formyl-...
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| Yayımlandı: | J Med Chem |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262926/ https://ncbi.nlm.nih.gov/pubmed/16722657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0601710 |
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