Llwytho...

5-(Dimethoxymethyl)-2′-Deoxyuridine: A Novel Gem Diether Nucleoside with Anti-Orthopoxvirus Activity

To provide potential new leads for the treatment of orthopoxvirus infections, the 5-position of the pyrimidine nucleosides have been modified with a gem diether moiety to yield the following new nucleosides: 5-(dimethoxymethyl)-2′-deoxyuridine (2b), 5-(diethoxymethyl)-2′-deoxyuridine (3b), 5-formyl-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Med Chem
Prif Awduron: Fan, Xuesen, Zhang, Xinying, Zhou, Longhu, Keith, Kathy A., Kern, Earl R., Torrence, Paul F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262926/
https://ncbi.nlm.nih.gov/pubmed/16722657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0601710
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