Non-invasive, Focused Ultrasound-Facilitated Gene Delivery for Optogenetics

per Wang, Shutao, Kugelman, Tara, Buch, Amanda, Herman, Mathieu, Han, Yang, Karakatsani, Maria Eleni, Hussaini, S. Abid, Duff, Karen, Konofagou, Elisa E.
Publicat a Sci Rep (2017)

Interplay between Cyclin-Dependent Kinase 5 and Glycogen Synthase Kinase 3β Mediated by Neuregulin Signaling Leads to Differential Effects on Tau Phosphorylation and Amyloid Precur...

per Wen, Yi, Planel, Emmanuel, Herman, Mathieu, Figueroa, Helen Y., Wang, Lili, Liu, Li, Lau, Lit-Fui, Yu, Wai Haung, Duff, Karen E.
Publicat a J Neurosci (2008)

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease

per Fu, Hongjun, Rodriguez, Gustavo A., Herman, Mathieu, Emrani, Sheina, Nahmani, Eden, Barrett, Geoffrey, Figueroa, Helen Y., Goldberg, Eliana, Hussaini, S. Abid, Duff, Karen E.
Publicat a Neuron (2017)

3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Age...

per Fu, Hongjun, Hussaini, S. Abid, Wegmann, Susanne, Profaci, Caterina, Daniels, Jacob D., Herman, Mathieu, Emrani, Sheina, Figueroa, Helen Y., Hyman, Bradley T., Davies, Peter, Duff, Karen E.
Publicat a PLoS One (2016)

Insulin Dysfunction Induces In Vivo Tau Hyperphosphorylation through Distinct Mechanisms

per Planel, Emmanuel, Tatebayashi, Yoshitaka, Miyasaka, Tomohiro, Liu, Li, Wang, Lili, Herman, Mathieu, Yu, W. Haung, Luchsinger, Jose A., Wadzinski, Brian, Duff, Karen E., Takashima, Akihiko
Publicat a J Neurosci (2007)

Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo

per Congdon, Erin E., Wu, Jessica W., Myeku, Natura, Figueroa, Yvette H., Herman, Mathieu, Marinec, Paul S., Gestwicki, Jason E., Dickey, Chad A., Yu, W. Haung, Duff, Karen E.
Publicat 2012

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Aβ accumulation

per Muhammad, Alim, Flores, Ingrid, Zhang, Hong, Yu, Rui, Staniszewski, Agnieszka, Planel, Emmanuel, Herman, Mathieu, Ho, Lingling, Kreber, Robert, Honig, Lawrence S., Ganetzky, Barry, Duff, Karen, Arancio, Ottavio, Small, Scott A.
Publicat 2008

Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons

per Wu, Jessica W., Herman, Mathieu, Liu, Li, Simoes, Sabrina, Acker, Christopher M., Figueroa, Helen, Steinberg, Joshua I., Margittai, Martin, Kayed, Rakez, Zurzolo, Chiara, Di Paolo, Gilbert, Duff, Karen E.
Publicat 2013

Anesthesia-Induced Hyperphosphorylation Detaches 3-Repeat Tau from Microtubules without Affecting Their Stability In Vivo

per Planel, Emmanuel, Krishnamurthy, Pavan, Miyasaka, Tomohiro, Liu, Li, Herman, Mathieu, Kumar, Asok, Bretteville, Alexis, Figueroa, Helen Y., Haung Yu, Wai, Whittington, Robert A., Davies, Peter, Takashima, Akihiko, Nixon, Ralph A., Duff, Karen E.
Publicat 2008

Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia

per Planel, Emmanuel, Richter, Karl E. G., Nolan, Charles E., Finley, James E., Liu, Li, Wen, Yi, Krishnamurthy, Pavan, Herman, Mathieu, Wang, Lili, Schachter, Joel B., Nelson, Robert B., Lau, Lit-Fui, Duff, Karen E.
Publicat a J Neurosci (2007)

Transcriptional regulation of β-secretase by p25/cdk5 leads to enhanced amyloidogenic processing

per Wen, Yi, Yu, W. Haung, Maloney, Bryan, Bailey, Jason, Ma, Junrong, Marié, Isabelle, Maurin, Thomas, Wang, Lili, Figueroa, Helen, Herman, Mathieu, Krishnamurthy, Pavan, Liu, Li, Planel, Emmanuel, Lau, Lit-Fui, Lahiri, Debomoy K., Duff, Karen
Publicat 2008

Excess Synaptojanin 1 Contributes to Place Cell Dysfunction and Memory Deficits in the Aging Hippocampus in Three Types of Alzheimer’s Disease

per Miranda, Andre M., Herman, Mathieu, Cheng, Rong, Nahmani, Eden, Barrett, Geoffrey, Micevska, Elizabeta, Fontaine, Gaelle, Potier, Marie-Claude, Head, Elizabeth, Schmitt, Frederick A., Lott, Ira T., Jiménez-Velázquez, Ivonne Z., Antonarakis, Stylianos E., Paolo, Gilbert Di, Lee, Joseph H., Hussaini, S. Abid, Marquer, Catherine
Publicat a Cell Rep (2018)

Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology

per Nuriel, Tal, Angulo, Sergio L., Khan, Usman, Ashok, Archana, Chen, Qiuying, Figueroa, Helen Y., Emrani, Sheina, Liu, Li, Herman, Mathieu, Barrett, Geoffrey, Savage, Valerie, Buitrago, Luna, Cepeda-Prado, Efrain, Fung, Christine, Goldberg, Eliana, Gross, Steven S., Hussaini, S. Abid, Moreno, Herman, Small, Scott A., Duff, Karen E.
Publicat a Nat Commun (2017)

Neuronal activity enhances tau propagation and tau pathology in vivo

per Wu, Jessica W., Hussaini, Syed A., Bastille, Isle M., Rodriguez, Gustavo A., Mrejeru, Ana, Rilett, Kelly, Sanders, David W., Cook, Casey, Fu, Hongjun, Boonen, Rick A.C.M., Herman, Mathieu, Nahmani, Eden, Emrani, Sheina, Helen Figueroa, Y., Diamond, Marc I., Clelland, Catherine L., Wray, Selina, Duff, Karen E.
Publicat a Nat Neurosci (2016)