Insulin Dysfunction Induces In Vivo Tau Hyperphosphorylation through Distinct Mechanisms

Hyperphosphorylated tau is the major component of paired helical filaments in neurofibrillary tangles found in Alzheimer's disease (AD) brains, and tau hyperphosphorylation is thought to be a critical event in the pathogenesis of the disease. The large majority of AD cases is late onset and spo...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Planel, Emmanuel, Tatebayashi, Yoshitaka, Miyasaka, Tomohiro, Liu, Li, Wang, Lili, Herman, Mathieu, Yu, W. Haung, Luchsinger, Jose A., Wadzinski, Brian, Duff, Karen E., Takashima, Akihiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2007
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673606/
https://ncbi.nlm.nih.gov/pubmed/18077675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3949-07.2007
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