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Insulin Dysfunction Induces In Vivo Tau Hyperphosphorylation through Distinct Mechanisms
Hyperphosphorylated tau is the major component of paired helical filaments in neurofibrillary tangles found in Alzheimer's disease (AD) brains, and tau hyperphosphorylation is thought to be a critical event in the pathogenesis of the disease. The large majority of AD cases is late onset and spo...
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| Izdano u: | J Neurosci |
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| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673606/ https://ncbi.nlm.nih.gov/pubmed/18077675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3949-07.2007 |
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