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Insulin Dysfunction Induces In Vivo Tau Hyperphosphorylation through Distinct Mechanisms

Hyperphosphorylated tau is the major component of paired helical filaments in neurofibrillary tangles found in Alzheimer's disease (AD) brains, and tau hyperphosphorylation is thought to be a critical event in the pathogenesis of the disease. The large majority of AD cases is late onset and spo...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Planel, Emmanuel, Tatebayashi, Yoshitaka, Miyasaka, Tomohiro, Liu, Li, Wang, Lili, Herman, Mathieu, Yu, W. Haung, Luchsinger, Jose A., Wadzinski, Brian, Duff, Karen E., Takashima, Akihiko
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2007
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673606/
https://ncbi.nlm.nih.gov/pubmed/18077675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3949-07.2007
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