Non-invasive, Focused Ultrasound-Facilitated Gene Delivery for Optogenetics

Optogenetics, a widely used technique in neuroscience research, is often limited by its invasive nature of application. Here, we present a noninvasive, ultrasound-based technique to introduce optogenetic channels into the brain by temporarily opening the blood-brain barrier (BBB). We demonstrate the...

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Pubblicato in:Sci Rep
Autori principali: Wang, Shutao, Kugelman, Tara, Buch, Amanda, Herman, Mathieu, Han, Yang, Karakatsani, Maria Eleni, Hussaini, S. Abid, Duff, Karen, Konofagou, Elisa E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216389/
https://ncbi.nlm.nih.gov/pubmed/28059117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39955
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