Amelioration of the nigrostriatal pathway facilitated by ultrasound-mediated neurotrophic delivery in early Parkinson’s Disease

The blood-brain barrier (BBB) prevents most drugs from gaining access to the brain parenchyma, which is a recognized impediment to the treatment of neurodegenerative disorders like Parkinson’s disease (PD). Focused ultrasound (FUS), in conjunction with systemically administered microbubbles, opens t...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Karakatsani, Maria Eleni, Wang, Shutao, Samiotaki, Gesthimani, Kugelman, Tara, Olumolade, Oluyemi O., Acosta, Camilo, Sun, Tao, Han, Yang, Kamimura, Hermes A. S., Jackson-Lewis, Vernice, Przedborski, Serge, Konofagou, Elisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618306/
https://ncbi.nlm.nih.gov/pubmed/30953664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.03.030
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