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Blood-Brain Barrier Opening in Behaving Non-Human Primates via Focused Ultrasound with Systemically Administered Microbubbles

Over the past fifteen years, focused ultrasound coupled with intravenously administered microbubbles (FUS) has been proven an effective, non-invasive technique to open the blood-brain barrier (BBB) in vivo. Here we show that FUS can safely and effectively open the BBB at the basal ganglia and thalam...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Downs, Matthew E., Buch, Amanda, Karakatsani, Maria Eleni, Konofagou, Elisa E., Ferrera, Vincent P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620488/
https://ncbi.nlm.nih.gov/pubmed/26496829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15076
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