Selective vulnerability in neurodegenerative diseases

per Fu, Hongjun, Hardy, John, Duff, Karen E.
Publicat a Nat Neurosci (2018)

Function of WFS1 and WFS2 in the Central Nervous System: Implications for Wolfram Syndrome and Alzheimer’s Disease

per Li, Liangping, Venkataraman, Lalitha, Chen, Shuo, Fu, Hongjun
Publicat a Neurosci Biobehav Rev (2020)

Use of scREAD to explore and analyze single-cell and single-nucleus RNA-seq data for Alzheimer’s disease

per Wang, Cankun, Xiang, Yujia, Fu, Hongjun, Ma, Qin
Publicat a STAR Protoc (2021)

Microglia do not take up soluble amyloid-beta peptides, but partially degrade them by secreting insulin-degrading enzyme

per Fu, Hongjun, Liu, Bin, Li, Liangping, Lemere, Cynthia A.
Publicat a Neuroscience (2020)

scREAD: A Single-Cell RNA-Seq Database for Alzheimer's Disease

per Jiang, Jing, Wang, Cankun, Qi, Ren, Fu, Hongjun, Ma, Qin
Publicat a iScience (2020)

Modeling neurodegenerative diseases with cerebral organoids and other three-dimensional culture systems: focus on Alzheimer’s disease

per Venkataraman, Lalitha, Fair, Summer R., McElroy, Craig A., Hester, Mark E., Fu, Hongjun
Publicat a Stem Cell Rev Rep (2020)

Environmental Novelty Activates β(2)-Adrenergic Signaling to Prevent the Impairment of Hippocampal LTP by Aβ Oligomers

per Li, Shaomin, Jin, Ming, Zhang, Dainan, Yang, Ting, Koeglsperger, Thomas, Fu, Hongjun, Selkoe, Dennis J.
Publicat 2013

MER5101, a Novel Aβ1-15:DT Conjugate Vaccine, Generates a Robust Anti-Aβ Antibody Response and Attenuates Aβ Pathology and Cognitive Deficits in APPswe/PS1ΔE9 Transgenic Mice

per Liu, Bin, Frost, Jeffrey L., Sun, Jing, Fu, Hongjun, Grimes, Stephen, Blackburn, Peter, Lemere, Cynthia A.
Publicat 2013

Role of Synaptic Structural Plasticity in Impairments of Spatial Learning and Memory Induced by Developmental Lead Exposure in Wistar Rats

per Xiao, Yongmei, Fu, Hongjun, Han, Xiaojie, Hu, Xiaoxia, Gu, Huaiyu, Chen, Yilin, Wei, Qing, Hu, Qiansheng
Publicat a PLoS One (2014)

Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy

per Fung, Christine W., Guo, Jia, Fu, Hongjun, Figueroa, Helen Y., Konofagou, Elisa E., Duff, Karen E.
Publicat a Sci Adv (2020)

Prediction method of vertical sealing evolution form and distribution position of oil source faults

per Fan Zili, Fu Hongjun, Fan Xiaodong, Xiao Hongwei, Guo Xiaobo, Ding Yi, Liu Peng, Liang Mugui
Publicat 2025-09-01

Future Extreme Precipitation Estimation in Inner Mongolia Autonomous Region Based on NEX-GDDP-CMIP6

per LI Xiaofeifan, WANG Yunlu, FU Hongjun, LUO Yimeng, XIAO Zihang, CHEN Li, LIU Ting, CUI Xinyu
Publicat 2025-01-01

scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses

per Wang, Juexin, Ma, Anjun, Chang, Yuzhou, Gong, Jianting, Jiang, Yuexu, Qi, Ren, Wang, Cankun, Fu, Hongjun, Ma, Qin, Xu, Dong
Publicat a Nat Commun (2021)

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease

per Fu, Hongjun, Rodriguez, Gustavo A., Herman, Mathieu, Emrani, Sheina, Nahmani, Eden, Barrett, Geoffrey, Figueroa, Helen Y., Goldberg, Eliana, Hussaini, S. Abid, Duff, Karen E.
Publicat a Neuron (2017)

3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Age...

per Fu, Hongjun, Hussaini, S. Abid, Wegmann, Susanne, Profaci, Caterina, Daniels, Jacob D., Herman, Mathieu, Emrani, Sheina, Figueroa, Helen Y., Hyman, Bradley T., Davies, Peter, Duff, Karen E.
Publicat a PLoS One (2016)

Complement Component C3 and Complement Receptor Type 3 Contribute to the Phagocytosis and Clearance of Fibrillar Aβ by Microglia

per Fu, Hongjun, Liu, Bin, Frost, Jeffrey L., Hong, Soyon, Jin, Ming, Ostaszewski, Beth, Shankar, Ganesh M., Costantino, Isabel M., Carroll, Michael C., Mayadas, Tanya N., Lemere, Cynthia A.
Publicat 2012

Pathologically Activated Neuroprotection via Uncompetitive Blockade of N-Methyl-d-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin

per Luo, Jialie, Li, Wenming, Zhao, Yuming, Fu, Hongjun, Ma, Dik-Lung, Tang, Jing, Li, Chaoying, Peoples, Robert W., Li, Fushun, Wang, Qinwen, Huang, Pingbo, Xia, Jun, Pang, Yuanping, Han, Yifan
Publicat 2010

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase

per Vo, My-Nuong, Terrey, Markus, Lee, Jeong Woong, Roy, Bappaditya, Moresco, James J., Sun, Litao, Fu, Hongjun, Liu, Qi, Weber, Thomas G., Yates, John R., Fredrick, Kurt, Schimmel, Paul, Ackerman, Susan L.
Publicat a Nature (2018)

A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology

per Fu, Hongjun, Possenti, Andrea, Freer, Rosie, Nakano, Yoshikazu, Hernandez Villegas, Nancy C., Tang, Maoping, Cauhy, Paula V. M, Lassus, Benjamin A., Chen, Shuo, Fowler, Stephanie L., Figueroa, Helen Y., Huey, Edward D., Johnson, Gail V.W., Vendruscolo, Michele, Duff, Karen E.
Publicat a Nat Neurosci (2018)

Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin

per Chang, Lan, Cui, Wei, Yang, Yong, Xu, Shujun, Zhou, Wenhua, Fu, Hongjun, Hu, Shengquan, Mak, Shinghung, Hu, Juwei, Wang, Qin, Pui-Yan Ma, Victor, Chung-lit Choi, Tony, Dik-lung Ma, Edmond, Tao, Liang, Pang, Yuanping, Rowan, Michael J., Anwyl, Roger, Han, Yifan, Wang, Qinwen
Publicat a Sci Rep (2015)