Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction and Spatial Memory Deficits Reminiscent of Early Alzheimer's Disease

Por Fu, Hongjun, Rodriguez, Gustavo A., Herman, Mathieu, Emrani, Sheina, Nahmani, Eden, Barrett, Geoffrey, Figueroa, Helen Y., Goldberg, Eliana, Hussaini, S. Abid, Duff, Karen E.
Publicado no Neuron (2017)

3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Age...

Por Fu, Hongjun, Hussaini, S. Abid, Wegmann, Susanne, Profaci, Caterina, Daniels, Jacob D., Herman, Mathieu, Emrani, Sheina, Figueroa, Helen Y., Hyman, Bradley T., Davies, Peter, Duff, Karen E.
Publicado no PLoS One (2016)

The Endosomal–Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo

Por Nuriel, Tal, Peng, Katherine Y., Ashok, Archana, Dillman, Allissa A., Figueroa, Helen Y., Apuzzo, Justin, Ambat, Jayanth, Levy, Efrat, Cookson, Mark R., Mathews, Paul M., Duff, Karen E.
Publicado no Front Neurosci (2017)

Anesthesia-Induced Hyperphosphorylation Detaches 3-Repeat Tau from Microtubules without Affecting Their Stability In Vivo

Por Planel, Emmanuel, Krishnamurthy, Pavan, Miyasaka, Tomohiro, Liu, Li, Herman, Mathieu, Kumar, Asok, Bretteville, Alexis, Figueroa, Helen Y., Haung Yu, Wai, Whittington, Robert A., Davies, Peter, Takashima, Akihiko, Nixon, Ralph A., Duff, Karen E.
Publicado em 2008

Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology

Por Nuriel, Tal, Angulo, Sergio L., Khan, Usman, Ashok, Archana, Chen, Qiuying, Figueroa, Helen Y., Emrani, Sheina, Liu, Li, Herman, Mathieu, Barrett, Geoffrey, Savage, Valerie, Buitrago, Luna, Cepeda-Prado, Efrain, Fung, Christine, Goldberg, Eliana, Gross, Steven S., Hussaini, S. Abid, Moreno, Herman, Small, Scott A., Duff, Karen E.
Publicado no Nat Commun (2017)