A Critical Evaluation of the Ubiquitin-Proteasome System in Parkinson's Disease

Por Cook, Casey, Petrucelli, Leonard
Publicado em 2009

Disruption of Protein Quality Control in Parkinson’s Disease

Por Cook, Casey, Stetler, Caroline, Petrucelli, Leonard
Publicado em 2012

The Ubiquitin-Proteasome Reporter GFPu Does Not Accumulate in Neurons of the R6/2 Transgenic Mouse Model of Huntington's Disease

Por Bett, John S., Cook, Casey, Petrucelli, Leonard, Bates, Gillian P.
Publicado em 2009

Acetylation: a new key to unlock tau’s role in neurodegeneration

Por Cook, Casey, Stankowski, Jeannette N, Carlomagno, Yari, Stetler, Caroline, Petrucelli, Leonard
Publicado em 2014

TDP-43 in Neurodegenerative Disorders

Por Cook, Casey, Zhang, Yong-Jie, Xu, Ya-fei, Dickson, Dennis W., Petrucelli, Leonard
Publicado em 2008

Loss of HDAC6, a novel CHIP substrate, alleviates abnormal tau accumulation

Por Cook, Casey, Gendron, Tania F., Scheffel, Kristyn, Carlomagno, Yari, Dunmore, Judy, DeTure, Michael, Petrucelli, Leonard
Publicado em 2012

TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor

Por Mohagheghi, Fatemeh, Prudencio, Mercedes, Stuani, Cristiana, Cook, Casey, Jansen-West, Karen, Dickson, Dennis W., Petrucelli, Leonard, Buratti, Emanuele
Publicado no Hum Mol Genet (2016)

Aging Is Not Associated with Proteasome Impairment in UPS Reporter Mice

Por Cook, Casey, Gass, Jennifer, Dunmore, Judith, Tong, Jimei, Taylor, Julie, Eriksen, Jason, McGowan, Eileen, Lewis, Jada, Johnston, Jennifer, Petrucelli, Leonard
Publicado em 2009

Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance

Por Cook, Casey, Carlomagno, Yari, Gendron, Tania F., Dunmore, Judy, Scheffel, Kristyn, Stetler, Caroline, Davis, Mary, Dickson, Dennis, Jarpe, Matthew, DeTure, Michael, Petrucelli, Leonard
Publicado em 2014

Casein Kinase II Induced Polymerization of Soluble TDP-43 into Filaments Is Inhibited by Heat Shock Proteins

Por Carlomagno, Yari, Zhang, Yongjie, Davis, Mary, Lin, Wen-Lang, Cook, Casey, Dunmore, Judy, Tay, William, Menkosky, Kyle, Cao, Xiangkun, Petrucelli, Leonard, DeTure, Michael
Publicado em 2014

Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau

Por Kang, Silvia S., Ebbert, Mark T.W., Baker, Kelsey E., Cook, Casey, Wang, Xuewei, Sens, Jonathon P., Kocher, Jeanne-Pierre, Petrucelli, Leonard, Fryer, John D.
Publicado no J Exp Med (2018)

Progranulin regulates neuronal outgrowth independent of Sortilin

Por Gass, Jennifer, Lee, Wing C, Cook, Casey, Finch, Nicole, Stetler, Caroline, Jansen-West, Karen, Lewis, Jada, Link, Christopher D, Rademakers, Rosa, Nykjær, Anders, Petrucelli, Leonard
Publicado em 2012

An acetylation–phosphorylation switch that regulates tau aggregation propensity and function

Por Carlomagno, Yari, Chung, Dah-eun Chloe, Yue, Mei, Castanedes-Casey, Monica, Madden, Benjamin J., Dunmore, Judy, Tong, Jimei, DeTure, Michael, Dickson, Dennis W., Petrucelli, Leonard, Cook, Casey
Publicado no J Biol Chem (2017)

Tau exhibits unique seeding properties in globular glial tauopathy

Por Chung, Dah-eun Chloe, Carlomagno, Yari, Cook, Casey N., Jansen-West, Karen, Daughrity, Lillian, Lewis-Tuffin, Laura J., Castanedes-Casey, Monica, DeTure, Michael, Dickson, Dennis W., Petrucelli, Leonard
Publicado no Acta Neuropathol Commun (2019)

Severe amygdala dysfunction in a MAPT transgenic mouse model of frontotemporal dementia

Por Cook, Casey, Dunmore, Judy H., Murray, Melissa E., Scheffel, Kristyn, Shukoor, Nawsheen, Tong, Jimei, Castanedes-Casey, Monica, Phillips, Virginia, Rousseau, Linda, Penuliar, Michael S., Kurti, Aishe, Dickson, Dennis W., Petrucelli, Leonard, Fryer, John D.
Publicado em 2013

The lysosomal protein cathepsin L is a progranulin protease

Por Lee, Chris W., Stankowski, Jeannette N., Chew, Jeannie, Cook, Casey N., Lam, Ying-Wai, Almeida, Sandra, Carlomagno, Yari, Lau, Kwok-Fai, Prudencio, Mercedes, Gao, Fen-Biao, Bogyo, Matthew, Dickson, Dennis W., Petrucelli, Leonard
Publicado no Mol Neurodegener (2017)

Posttranslational modifications mediate the structural diversity of tauopathy strains

Por Arakhamia, Tamta, Lee, Christina E., Carlomagno, Yari, Duong, Duc M., Kundinger, Sean R., Wang, Kevin, Williams, Dewight, DeTure, Michael, Dickson, Dennis W., Cook, Casey N., Seyfried, Nicholas T., Petrucelli, Leonard, Fitzpatrick, Anthony W. P.
Publicado no Cell (2020)

Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model

Por Cook, Casey, Kang, Silvia S., Carlomagno, Yari, Lin, Wen-Lang, Yue, Mei, Kurti, Aishe, Shinohara, Mitsuru, Jansen-West, Karen, Perkerson, Emilie, Castanedes-Casey, Monica, Rousseau, Linda, Phillips, Virginia, Bu, Guojun, Dickson, Dennis W., Petrucelli, Leonard, Fryer, John D.
Publicado no Hum Mol Genet (2015)

Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD.

Por Goodman, Lindsey D., Prudencio, Mercedes, Kramer, Nicholas J., Martinez-Ramirez, Luis F., Srinivasan, Ananth R., Lan, Matthews, Parisi, Michael J., Zhu, Yongqing, Chew, Jeannie, Cook, Casey N., Berson, Amit, Gitler, Aaron D., Petrucelli, Leonard, Bonini, Nancy M.
Publicado no Nat Neurosci (2019)

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Por Chew, Jeannie, Cook, Casey, Gendron, Tania F., Jansen-West, Karen, del Rosso, Giulia, Daughrity, Lillian M., Castanedes-Casey, Monica, Kurti, Aishe, Stankowski, Jeannette N., Disney, Matthew D., Rothstein, Jeffrey D., Dickson, Dennis W., Fryer, John D., Zhang, Yong-Jie, Petrucelli, Leonard
Publicado no Mol Neurodegener (2019)