Aging Is Not Associated with Proteasome Impairment in UPS Reporter Mice

BACKGROUND: Covalent linkage of ubiquitin regulates the function and, ultimately, the degradation of many proteins by the ubiquitin-proteasome system (UPS). Given its essential role in protein regulation, even slight perturbations in UPS activity can substantially impair cellular function. METHODOLO...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Cook, Casey, Gass, Jennifer, Dunmore, Judith, Tong, Jimei, Taylor, Julie, Eriksen, Jason, McGowan, Eileen, Lewis, Jada, Johnston, Jennifer, Petrucelli, Leonard
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2009
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690827/
https://ncbi.nlm.nih.gov/pubmed/19517018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005888
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla