Progranulin regulates neuronal outgrowth independent of Sortilin

BACKGROUND: Progranulin (PGRN), a widely secreted growth factor, is involved in multiple biological functions, and mutations located within the PGRN gene (GRN) are a major cause of frontotemporal lobar degeneration with TDP-43-positive inclusions (FLTD-TDP). In light of recent reports suggesting PGR...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gass, Jennifer, Lee, Wing C, Cook, Casey, Finch, Nicole, Stetler, Caroline, Jansen-West, Karen, Lewis, Jada, Link, Christopher D, Rademakers, Rosa, Nykjær, Anders, Petrucelli, Leonard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508877/
https://ncbi.nlm.nih.gov/pubmed/22781549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-33
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados