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Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau
Alzheimer’s disease (AD) is an age-associated neurodegenerative disease characterized by amyloidosis, tauopathy, and activation of microglia, the brain resident innate immune cells. We show that a RiboTag translational profiling approach can bypass biases due to cellular enrichment/cell sorting. Usi...
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| Veröffentlicht in: | J Exp Med |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6122978/ https://ncbi.nlm.nih.gov/pubmed/30082275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180653 |
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