A computational design approach for virtual screening of peptide interactions across K(+) channel families()

Yazar: Doupnik, Craig A., Parra, Katherine C., Guida, Wayne C.
Yayımlandı Comput Struct Biotechnol J (2014)

In silico characterization of an atypical MAPK phosphatase of Plasmodium falciparum as a suitable target for drug discovery

Yazar: Campbell, Christopher O., Santiago, Daniel N., Guida, Wayne C., Manetsch, Roman, Adams, John H.
Yayımlandı Chem Biol Drug Des (2014)

Substitution of aminomethyl at the meta- position enhances the inactivation of O(6)-alkylguanine-DNA alkyltransferase by O(6)-benzylguanine

Yazar: Pauly, Gary T., Loktionova, Natalia A., Fang, Qingming, Vankayala, Sai Lakshmana, Guida, Wayne C., Pegg, Anthony E.
Baskı/Yayın Bilgisi 2008

Role of the Sulfonium Center in Determining Ligand Specificity of Human S-Adenosylmethionine Decarboxylase

Yazar: Bale, Shridhar, Brooks, Wesley, Hanes, Jeremiah W., Mahesan, Arnold M., Guida, Wayne C., Ealick, Steven E.
Baskı/Yayın Bilgisi 2009

Production of recombinant 1-deoxy-d-xylulose-5-phosphate synthase from Plasmodium vivax in Escherichia coli()

Yazar: Handa, Sumit, Ramamoorthy, Divya, Spradling, Tyler J., Guida, Wayne C., Adams, John H., Bendinskas, Kestutis G., Merkler, David J.
Baskı/Yayın Bilgisi 2013

Oxadiazole-isopropylamides as Potent and Non-covalent Proteasome Inhibitors

Yazar: Ozcan, Sevil, Kazi, Aslamuzzaman, Marsilio, Frank, Fang, Bin, Guida, Wayne C., Koomen, John, Lawrence, Harshani R., Sebti, Saïd M.
Baskı/Yayın Bilgisi 2013

β-Strand mimics based on tetrahydropyridazinedione (tpd) peptide stitching

Yazar: Kang, Chang Won, Sarnowski, Matthew P., Ranatunga, Sujeewa, Wojtas, Lukasz, Metcalf, Rainer S., Guida, Wayne C., Del Valle, Juan R.
Yayımlandı Chem Commun (Camb) (2015)

Discovery of a novel proteasome inhibitor selective for cancer cells over non-transformed cells

Yazar: Kazi, Aslamuzzaman, Lawrence, Harshani, Guida, Wayne C, McLaughlin, Mark L, Springett, Gregory M, Berndt, Norbert, Yip, Richard M, Sebti, Saïd M
Baskı/Yayın Bilgisi 2009

An Allosteric Binding Site on Sortilin Regulates the Trafficking of VLDL, PCSK9 and LDLR in Hepatocytes

Yazar: Sparks, Robert P., Arango, Andres S., Jenkins, Jermaine L., Guida, Wayne C., Tajkhorshid, Emad, Sparks, Charles E., Sparks, Janet D., Fratti, Rutilio A.
Yayımlandı Biochemistry (2020)

A Facile Iterative Synthesis of 2,5-Terpyrimidinylenes as Non-peptidic α-Helical Mimics

Yazar: Anderson, Laura, Zhou, Mingzhou, Sharma, Vasudha, McLaughlin, Jillian M., Santiago, Daniel N., Fronczek, Frank R., Guida, Wayne C., McLaughlin, Mark L.
Baskı/Yayın Bilgisi 2010

Synthesis and Biological Evaluation of Naphthoquinone Analogs as a Novel Class of Proteasome Inhibitors

Yazar: Lawrence, Harshani R., Kazi, Aslamuzzaman, Luo, Yunting, Kendig, Robert, Ge, Yiyu, Jain, Sanjula, Daniel, Kenyon, Santiago, Daniel, Guida, Wayne C., Sebti, Saïd M.
Baskı/Yayın Bilgisi 2010

Development of new N-Arylbenzamides as STAT3 Dimerization Inhibitors

Yazar: Urlam, Murali K., Pireddu, Roberta, Ge, Yiyu, Zhang, Xiaolei, Sun, Ying, Lawrence, Harshani R., Guida, Wayne C., Sebti, Saïd M., Lawrence, Nicholas J.
Baskı/Yayın Bilgisi 2013

A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation

Yazar: Zhang, Xiaolei, Sun, Ying, Pireddu, Roberta, Yang, Hua, Urlam, Murali K., Lawrence, Harshani R., Guida, Wayne C., Lawrence, Nicholas J., Sebti, Saïd M.
Baskı/Yayın Bilgisi 2013

Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding

Yazar: Sparks, Robert P., Jenkins, Jermaine L., Miner, Gregory E., Wang, Yan, Guida, Wayne C., Sparks, Charles E., Fratti, Rutilio A., Sparks, Janet D.
Yayımlandı Biochem Biophys Res Commun (2016)

Discovery and Synthesis of Hydronaphthoquinones as Novel Proteasome Inhibitors

Yazar: Ge, Yiyu, Kazi, Aslamuzzaman, Marsilio, Frank, Luo, Yunting, Jain, Sanjula, Brooks, Wesley, Daniel, Kenyon G., Guida, Wayne C., Sebti, Saïd M., Lawrence, Harshani R.
Baskı/Yayın Bilgisi 2012

Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells

Yazar: Sparks, Robert P., Guida, Wayne C., Sowden, Mark P., Jenkins, Jermaine L., Starr, Matthew L., Fratti, Rutilio A., Sparks, Charles E., Sparks, Janet D.
Yayımlandı Biochem Biophys Res Commun (2016)

Mechanistic Studies of 1-Deoxy-D-Xylulose-5-Phosphate Synthase from Deinococcus radiodurans

Yazar: Handa, Sumit, Dempsey, Daniel R, Ramamoorthy, Divya, Cook, Nanci, Guida, Wayne C, Spradling, Tyler J, White, Justin K, Woodcock, H Lee, Merkler, David J
Yayımlandı Biochem Mol Biol J (2018)

Shp2 protein tyrosine phosphatase inhibitor activity of estramustine phosphate and its triterpenoid analogs

Yazar: Scott, Latanya M., Chen, Liwei, Daniel, Kenyon G., Brooks, Wesley H., Guida, Wayne C., Lawrence, Harshani R., Sebti, Said M., Lawrence, Nicholas J., Wu, Jie
Baskı/Yayın Bilgisi 2010

New Insights into the Design of Inhibitors of Human S-Adenosylmethionine Decarboxylase: Studies of Adenine C(8) Substitution in Structural Analogues of S-Adenosylmethionine

Yazar: McCloskey, Diane E., Bale, Shridhar, Secrist, John A., Tiwari, Anita, Moss, Thomas H., Valiyaveettil, Jacob, Brooks, Wesley H., Guida, Wayne C., Pegg, Anthony E., Ealick, Steven E.
Baskı/Yayın Bilgisi 2009

Virtual Target Screening: Validation Using Kinase Inhibitors

Yazar: Santiago, Daniel N., Pevzner, Yuri, Durand, Ashley A., Tran, MinhPhuong, Scheerer, Rachel R., Daniel, Kenyon, Sung, Shen-Shu, Woodcock, H. Lee, Guida, Wayne C., Brooks, Wesley H.
Baskı/Yayın Bilgisi 2012