RNA Interference-Mediated Silencing of Ornithine Decarboxylase and Spermidine Synthase Genes in Trypanosoma brucei Provides Insight into Regulation of Polyamine Biosynthesis

Por Xiao, Yanjing, McCloskey, Diane E., Phillips, Margaret A.
Publicado em 2009

Effect of spermine synthase on the sensitivity of cells to anti-tumour agents.

Por Ikeguchi, Yoshihiko, Mackintosh, Caroline A, McCloskey, Diane E, Pegg, Anthony E
Publicado em 2003

Complexes of Thermotoga maritima S-adenosylmethionine decarboxylase provide insights into substrate specificity

Por Bale, Shridhar, Baba, Kavita, McCloskey, Diane E., Pegg, Anthony E., Ealick, Steven E.
Publicado em 2010

The α9β1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channel

Por deHart, Gregory W., Jin, Taihao, McCloskey, Diane E., Pegg, Anthony E., Sheppard, Dean
Publicado em 2008

Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii

Por Soriano, Erika V., McCloskey, Diane E., Kinsland, Cynthia, Pegg, Anthony E., Ealick, Steven E.
Publicado em 2008

Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis

Por Welsh, Patricia A., Sass-Kuhn, Suzanne, Prakashagowda, Chethana, McCloskey, Diane E., Feith, David J.
Publicado em 2012

Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine

Por Šečkutė, Jolita, McCloskey, Diane E, Thomas, H Jeanette, Secrist, John A, Pegg, Anthony E, Ealick, Steven E
Publicado em 2011

S-adenosylmethionine decarboxylase overexpression inhibits mouse skin tumor promotion

Por Shi, Chenxu, Cooper, Timothy K., McCloskey, Diane E., Glick, Adam B., Shantz, Lisa M., Feith, David J.
Publicado em 2012

Characterization of transgenic mice with widespread overexpression of spermine synthase

Por Ikeguchi, Yoshihiko, Wang, Xiaojing, McCLOSKEY, Diane E., Coleman, Catherine S., Nelson, Paul, Hu, Guirong, Shantz, Lisa M., Pegg, Anthony E.
Publicado em 2004

Characterization of transgenic mice with overexpression of spermidine synthase

Por Shi, Chenxu, Welsh, Patricia A., Sass-Kuhn, Suzanne, Wang, Xiaojing, McCloskey, Diane E., Pegg, Anthony E., Feith, David J.
Publicado em 2011

Independent evolutionary origins of functional polyamine biosynthetic enzyme fusions catalyzing de novo diamine to triamine formation

Por Green, Robert, Hanfrey, Colin C., Elliott, Katherine A., McCloskey, Diane E., Wang, Xiaojing, Kanugula, Sreenivas, Pegg, Anthony E., Michael, Anthony J.
Publicado em 2011

Crystal Structure of Human Spermine Synthase: IMPLICATIONS OF SUBSTRATE BINDING AND CATALYTIC MECHANISM

Por Wu, Hong, Min, Jinrong, Zeng, Hong, McCloskey, Diane E., Ikeguchi, Yoshihiko, Loppnau, Peter, Michael, Anthony J., Pegg, Anthony E., Plotnikov, Alexander N.
Publicado em 2008

New Insights into the Design of Inhibitors of Human S-Adenosylmethionine Decarboxylase: Studies of Adenine C(8) Substitution in Structural Analogues of S-Adenosylmethionine

Por McCloskey, Diane E., Bale, Shridhar, Secrist, John A., Tiwari, Anita, Moss, Thomas H., Valiyaveettil, Jacob, Brooks, Wesley H., Guida, Wayne C., Pegg, Anthony E., Ealick, Steven E.
Publicado em 2009