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Complexes of Thermotoga maritima S-adenosylmethionine decarboxylase provide insights into substrate specificity

The polyamines putrescine, spermidine and spermine are ubiquitous aliphatic cations and are essential for cellular growth and differentiation. S-Adenosylmethionine decarboxylase (AdoMetDC) is a critical pyruvoyl-dependent enzyme in the polyamine-biosynthetic pathway. The crystal structures of AdoMet...

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Bibliographische Detailangaben
Hauptverfasser: Bale, Shridhar, Baba, Kavita, McCloskey, Diane E., Pegg, Anthony E., Ealick, Steven E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815669/
https://ncbi.nlm.nih.gov/pubmed/20124698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S090744490904877X
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