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Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase
[Image: see text] Putrescine (1,4-diaminobutane) activates the autoprocessing and decarboxylation reactions of human S-adenosylmethionine decarboxylase (AdoMetDC), a critical enzyme in the polyamine biosynthetic pathway. In human AdoMetDC, putrescine binds in a buried pocket containing acidic residu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646671/ https://ncbi.nlm.nih.gov/pubmed/19053272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801732m |
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