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The α9β1 integrin enhances cell migration by polyamine-mediated modulation of an inward-rectifier potassium channel
The α9β1 integrin accelerates cell migration through binding of spermidine/spermine acetyltransferase (SSAT) to the α9 cytoplasmic domain. We now show that SSAT enhances α9-mediated migration specifically through catabolism of spermidine and/or spermine. Because spermine and spermidine are effective...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2386075/ https://ncbi.nlm.nih.gov/pubmed/18480266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708044105 |
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