Independent evolutionary origins of functional polyamine biosynthetic enzyme fusions catalyzing de novo diamine to triamine formation

We have identified gene fusions of polyamine biosynthetic enzymes S-adenosylmethionine decarboxylase (AdoMetDC, speD) and aminopropyltransferase (speE) orthologues in diverse bacterial phyla. Both domains are functionally active and we demonstrate the novel de novo synthesis of the triamine spermidi...

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Detalhes bibliográficos
Main Authors: Green, Robert, Hanfrey, Colin C., Elliott, Katherine A., McCloskey, Diane E., Wang, Xiaojing, Kanugula, Sreenivas, Pegg, Anthony E., Michael, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196669/
https://ncbi.nlm.nih.gov/pubmed/21762220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07757.x
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