Effect of spermine synthase on the sensitivity of cells to anti-tumour agents.

Por Ikeguchi, Yoshihiko, Mackintosh, Caroline A, McCloskey, Diane E, Pegg, Anthony E
Publicado em 2003

Enhancing Human Spermine Synthase Activity by Engineered Mutations

Por Zhang, Zhe, Zheng, Yueli, Petukh, Margo, Pegg, Anthony, Ikeguchi, Yoshihiko, Alexov, Emil
Publicado em 2013

Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells

Por Ishii, Ikumi, Ikeguchi, Yoshihiko, Mano, Hiroshi, Wada, Masahiro, Pegg, Anthony E., Shirahata, Akira
Publicado em 2011

Rational Design of Small-Molecule Stabilizers of Spermine Synthase Dimer by Virtual Screening and Free Energy-Based Approach

Por Zhang, Zhe, Martiny, Virginie, Lagorce, David, Ikeguchi, Yoshihiko, Alexov, Emil, Miteva, Maria A.
Publicado em 2014

A rational free energy-based approach to understanding and targeting disease-causing missense mutations

Por Zhang, Zhe, Witham, Shawn, Petukh, Marharita, Moroy, Gautier, Miteva, Maria, Ikeguchi, Yoshihiko, Alexov, Emil
Publicado em 2013

The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor

Por Korolev, Sergey, Ikeguchi, Yoshihiko, Skarina, Tatiana, Beasley, Steven, Arrowsmith, Cheryl, Edwards, Aled, Joachimiak, Andrzej, Pegg, Anthony E., Savchenko, Alexei
Publicado em 2002

Characterization of transgenic mice with widespread overexpression of spermine synthase

Por Ikeguchi, Yoshihiko, Wang, Xiaojing, McCLOSKEY, Diane E., Coleman, Catherine S., Nelson, Paul, Hu, Guirong, Shantz, Lisa M., Pegg, Anthony E.
Publicado em 2004

Crystal Structure of Human Spermine Synthase: IMPLICATIONS OF SUBSTRATE BINDING AND CATALYTIC MECHANISM

Por Wu, Hong, Min, Jinrong, Zeng, Hong, McCloskey, Diane E., Ikeguchi, Yoshihiko, Loppnau, Peter, Michael, Anthony J., Pegg, Anthony E., Plotnikov, Alexander N.
Publicado em 2008