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Enhancing Human Spermine Synthase Activity by Engineered Mutations
Spermine synthase (SMS) is an enzyme which function is to convert spermidine into spermine. It was shown that gene defects resulting in amino acid changes of the wild type SMS cause Snyder-Robinson syndrome, which is a mild-to-moderate mental disability associated with osteoporosis, facial asymmetry...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585406/ https://ncbi.nlm.nih.gov/pubmed/23468611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002924 |
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