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The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor

Polyamines are essential in all branches of life. Spermidine synthase (putrescine aminopropyltransferase, PAPT) catalyzes the biosynthesis of spermidine, a ubiquitous polyamine. The crystal structure of the PAPT from Thermotoga maritima (TmPAPT) has been solved to 1.5 Å resolution in the presence an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Korolev, Sergey, Ikeguchi, Yoshihiko, Skarina, Tatiana, Beasley, Steven, Arrowsmith, Cheryl, Edwards, Aled, Joachimiak, Andrzej, Pegg, Anthony E., Savchenko, Alexei
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792006/
https://ncbi.nlm.nih.gov/pubmed/11731804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsb737
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