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Characterization of transgenic mice with widespread overexpression of spermine synthase

A widespread increase in SpmS (spermine synthase) activity has been produced in transgenic mice using a construct in which the human SpmS cDNA was placed under the control of a composite CMV-IE (cytomegalovirus immediate early gene) enhancer–chicken β-actin promoter. Four separate founder CAG/SpmS m...

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Detalhes bibliográficos
Main Authors: Ikeguchi, Yoshihiko, Wang, Xiaojing, McCLOSKEY, Diane E., Coleman, Catherine S., Nelson, Paul, Hu, Guirong, Shantz, Lisa M., Pegg, Anthony E.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133879/
https://ncbi.nlm.nih.gov/pubmed/15104536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040419
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