β-Strand mimics based on tetrahydropyridazinedione (tpd) peptide stitching

Short peptides featuring a tetrahydropyridazinedione (tpd) backbone tether exhibit reduced conformational flexibility external to the heterocyclic constraint. Analysis by NMR, molecular modeling and X-ray crystallography suggests both covalent and non-covalent stabilization of extended peptide confo...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Chem Commun (Camb)
Asıl Yazarlar: Kang, Chang Won, Sarnowski, Matthew P., Ranatunga, Sujeewa, Wojtas, Lukasz, Metcalf, Rainer S., Guida, Wayne C., Del Valle, Juan R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561724/
https://ncbi.nlm.nih.gov/pubmed/26400240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc07189e
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