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Synthesis and Conformational Analysis of Bicyclic Extended Dipeptide Surrogates
Regio- and diastereoselective reactions of a homoproline enolate enable the synthesis of novel extended dipeptide surrogates. Bicyclic carbamate 9 and fused β-lactam scaffold 11 were prepared from L-pyroglutamic acid via substrate-controlled electrophilic azidation. Synthesis of orthogonally-protect...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914495/ https://ncbi.nlm.nih.gov/pubmed/20593836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo1008433 |
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