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Solid-Phase Synthesis of Tetrahydropyridazinedione-Constrained Peptides
[Image: see text] The design and solid-phase synthesis of tetrahydropyridazine-3,6-dione (Tpd) peptidomimetics derived from backbone-aminated peptides is reported. The described protocol features the synthesis of chiral α-hydrazino acids suitable for chemoselective incorporation into growing peptide...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201324/ https://ncbi.nlm.nih.gov/pubmed/25295511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol5026684 |
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