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β-Strand mimics based on tetrahydropyridazinedione (tpd) peptide stitching
Short peptides featuring a tetrahydropyridazinedione (tpd) backbone tether exhibit reduced conformational flexibility external to the heterocyclic constraint. Analysis by NMR, molecular modeling and X-ray crystallography suggests both covalent and non-covalent stabilization of extended peptide confo...
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| Publicado no: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5561724/ https://ncbi.nlm.nih.gov/pubmed/26400240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc07189e |
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