Peptide folding driven by Van der Waals interactions

по Sung, Shen-Shu
Опубликовано в: Protein Sci (2015)

Dielectric screening effect of electronic polarization and intramolecular hydrogen bonding

по Sung, Shen‐Shu
Опубликовано в: Protein Sci (2017)

Targeting Sphingosine-1-Phosphate Receptors in Cancer

по Watters, Rebecca J., Wang, Hong-Gang, Sung, Shen-Shu, Loughran, Thomas P., Liu, Xin
Опубликовано 2011

Targeting of Chk2 as a countermeasure to dose-limiting toxicity triggered by topoisomerase-II (TOP2) poisons

по Gokare, Prashanth, Navaraj, Arunasalam, Zhang, Shengliang, Motoyama, Noboru, Sung, Shen-Shu, Finnberg, Niklas K.
Опубликовано в: Oncotarget (2016)

A SMALL MOLECULE E2F INHIBITOR BLOCKS GROWTH IN A MELANOMA CULTURE MODEL

по Ma, Yihong, Kurtyka, Courtney A., Boyapalle, Sandhya, Sung, Shen-Shu, Lawrence, Harshani, Guida, Wayne, Cress, W. Douglas
Опубликовано 2008

Characterization of a Novel Anti-Cancer Compound for Astrocytomas

по Lee, Sang Y., Slagle-Webb, Becky, Rizk, Elias, Patel, Akshal, Miller, Patti A., Sung, Shen-Shu, Connor, James R.
Опубликовано 2014

Pyoluteorin derivatives induce Mcl-1 degradation and apoptosis in hematological cancer cells

по Doi, Kenichiro, Gowda, Krishne, Liu, Qiang, Lin, Jyh-Ming, Sung, Shen-Shu, Dower, Christopher, Claxton, David, Loughran, Thomas P, Amin, Shantu, Wang, Hong-Gang
Опубликовано в: Cancer Biol Ther (2014)

Virtual Target Screening: Validation Using Kinase Inhibitors

по Santiago, Daniel N., Pevzner, Yuri, Durand, Ashley A., Tran, MinhPhuong, Scheerer, Rachel R., Daniel, Kenyon, Sung, Shen-Shu, Woodcock, H. Lee, Guida, Wayne C., Brooks, Wesley H.
Опубликовано 2012

The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-X(L), Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner

по Kazi, Aslamuzzaman, Sun, Jiazhi, Doi, Kenichiro, Sung, Shen-Shu, Takahashi, Yoshinori, Yin, Hang, Rodriguez, Johanna M., Becerril, Jorge, Berndt, Norbert, Hamilton, Andrew D., Wang, Hong-Gang, Sebti, Saïd M.
Опубликовано 2011

A novel selective multikinase inhibitor of ROCK and MRCK effectively blocks cancer cell migration and invasion

по Kale, Vijay Pralhad, Hengst, Jeremy A., Desai, Dhimant H., Dick, Taryn E., Choe, Katherine N., Colledge, Ashley L., Takahashi, Yoshinori, Sung, Shen-Shu, Amin, Shantu G., Yun, Jong K.
Опубликовано 2014

Inhibitors of Src Homology-2 Domain containing Protein Tyrosine Phosphatase-2 (Shp2) Based on Oxindole Scaffolds

по Lawrence, Harshani R., Pireddu, Roberta, Chen, Liwei, Luo, Yunting, Sung, Shen-Shu, Szymanski, Ann Marie, Richard Yip, M. L., Guida, Wayne C., Sebti, Saïd M., Wu, Jie, Lawrence, Nicholas J.
Опубликовано 2008

Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112

по Chen, Liwei, Pernazza, Daniele, Scott, Latanya M., Lawrence, Harshani R., Ren, Yuan, Luo, Yunting, Wu, Xin, Sung, Shen-Shu, Guida, Wayne C., Sebti, Said M., Lawrence, Nicholas J., Wu, Jie
Опубликовано 2010

Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2)

по Pireddu, Roberta, Forinash, Kara D., Sun, Nan N., Martin, Mathew P., Sung, Shen-Shu, Alexander, Brian, Zhu, Jin-Yi, Guida, Wayne C., Schönbrunn, Ernst, Sebti, Saïd M., Lawrence, Nicholas J.
Опубликовано 2012

The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines

по Dick, Taryn E., Hengst, Jeremy A., Fox, Todd E., Colledge, Ashley L., Kale, Vijay P., Sung, Shen-Shu, Sharma, Arun, Amin, Shantu, Loughran, Thomas P., Kester, Mark, Wang, Hong-Gang, Yun, Jong K.
Опубликовано в: J Pharmacol Exp Ther (2015)

Identification of a Disruptor of the MDM2-p53 Protein-Protein Interaction Facilitated by High-throughput in Silico Docking

по Lawrence, Harshani R., Li, Zhenyu, Yip, M.L. Richard, Sung, Shen-Shu, Lawrence, Nicholas J., McLaughlin, Mark L., McManus, Gregory J., Zaworotko, Michael J., Sebti, Saïd M., Chen, Jiandong, Guida, Wayne C.
Опубликовано 2009

Fragment-Based and Structure-Guided Discovery and Optimization of Rho Kinase Inhibitors

по Li, Rongshi, Martin, Mathew P., Liu, Yan, Wang, Binglin, Patel, Ronil A., Zhu, Jin-Yi, Sun, Nan, Pireddu, Roberta, Lawrence, Nicholas J., Li, Jiannong, Haura, Eric B., Sung, Shen-Shu, Guida, Wayne C., Schonbrunn, Ernst, Sebti, Said M.
Опубликовано в: J Med Chem (2012)

Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for Proteasomal Degradation

по Doi, Kenichiro, Li, Rongshi, Sung, Shen-Shu, Wu, Hongwei, Liu, Yan, Manieri, Wanda, Krishnegowda, Gowdahalli, Awwad, Andy, Dewey, Alden, Liu, Xin, Amin, Shantu, Cheng, Chunwei, Qin, Yong, Schonbrunn, Ernst, Daughdrill, Gary, Loughran, Thomas P., Sebti, Said, Wang, Hong-Gang
Опубликовано 2012