Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Cells

gan Gu, Mingxia
Cyhoeddwyd yn Curr Protoc Hum Genet (2018)

Small-conductance Ca(2+)-activated K(+) channels: insights into their roles in cardiovascular disease

gan Gu, Mingxia, Zhu, Yanrong, Yin, Xiaorong, Zhang, Dai-Min
Cyhoeddwyd yn Exp Mol Med (2018)

Large animal induced pluripotent stem cells as pre-clinical models for studying human disease

gan Plews, Jordan R, Gu, Mingxia, Longaker, Michael T, Wu, Joseph C
Cyhoeddwyd 2012

Generation of Quiescent Cardiac Fibroblasts from Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis

gan Zhang, Hao, Tian, Lei, Shen, Mengcheng, Tu, Chengyi, Wu, Haodi, Gu, Mingxia, Paik, David T., Wu, Joseph C.
Cyhoeddwyd yn Circ Res (2019)

A novel mechanism of γ/δ T-lymphocyte and endothelial activation by shear stress -- the role of ecto-ATP synthase β chain

gan Fu, Yi, Hou, Yingjian, Fu, Chenglai, Gu, Mingxia, Li, Chenghong, Kong, Wei, Wang, Xian, Shyy, John Y-J., Zhu, Yi
Cyhoeddwyd 2010

Activation of integrin α5 mediated by flow requires its translocation to membrane lipid rafts in vascular endothelial cells

gan Sun, Xiaoli, Fu, Yi, Gu, Mingxia, Zhang, Lu, Li, Dan, Li, Hongliang, Chien, Shu, Shyy, John Y.-J., Zhu, Yi
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2016)

Capillary cell type specialization in the alveolus

gan Gillich, Astrid, Zhang, Fan, Farmer, Colleen G., Travaglini, Kyle J., Tan, Serena Y., Gu, Mingxia, Zhou, Bin, Feinstein, Jeffrey A., Krasnow, Mark A., Metzger, Ross J.
Cyhoeddwyd yn Nature (2020)

In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and its Target Slug

gan Hopper, Rachel K., Moonen, Jan-Renier A.J., Diebold, Isabel, Cao, Aiqin, Rhodes, Christopher J., Tojais, Nancy F., Hennigs, Jan K., Gu, Mingxia, Wang, Lingli, Rabinovitch, Marlene
Cyhoeddwyd yn Circulation (2016)

Genome Editing of Isogenic Human Induced Pluripotent Stem Cells Recapitulates Long QT Phenotype for Drug Testing

gan Wang, Yongming, Liang, Ping, Lan, Feng, Wu, Haodi, Lisowski, Leszek, Gu, Mingxia, Hu, Shijun, Kay, Mark A., Urnov, Fyodor D., Shinnawi, Rami, Gold, Joseph D., Gepstein, Lior, Wu, Joseph C.
Cyhoeddwyd 2014

Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods

gan Churko, Jared M., Lee, Jaecheol, Ameen, Mohamed, Gu, Mingxia, Venkatasubramanian, Meenakshi, Diecke, Sebastian, Sallam, Karim, Im, Hogune, Wang, Gavin, Gold, Joseph D., Salomonis, Nathan, Snyder, Michael P., Wu, Joseph C.
Cyhoeddwyd yn Nat Biomed Eng (2017)

Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension

gan Reyes-Palomares, Armando, Gu, Mingxia, Grubert, Fabian, Berest, Ivan, Sa, Silin, Kasowski, Maya, Arnold, Christian, Shuai, Mao, Srivas, Rohith, Miao, Simon, Li, Dan, Snyder, Michael P., Rabinovitch, Marlene, Zaugg, Judith B.
Cyhoeddwyd yn Nat Commun (2020)

Pravastatin reverses obesity-induced dysfunction of induced pluripotent stem cell-derived endothelial cells via a nitric oxide-dependent mechanism

gan Gu, Mingxia, Mordwinkin, Nicholas M., Kooreman, Nigel G., Lee, Jaecheol, Wu, Haodi, Hu, Shijun, Churko, Jared M., Diecke, Sebastian, Burridge, Paul W., He, Chunjiang, Barron, Frances E., Ong, Sang-Ging, Gold, Joseph D., Wu, Joseph C.
Cyhoeddwyd yn Eur Heart J (2015)

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy

gan Wu, Haodi, Lee, Jaecheol, Vincent, Ludovic G., Wang, Qingtong, Gu, Mingxia, Lan, Feng, Churko, Jared, Sallam, Karim, Matsa, Elena, Sharma, Arun, Gold, Joseph D., Engler, Adam J., Xiang, Yang K., Bers, Donald M., Wu, Joseph C.
Cyhoeddwyd yn Cell Stem Cell (2015)

BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer–promoter activity and maintains pluripotency

gan Niu, Cong, Wang, Siqing, Guo, Jieyu, Wei, Xiangxiang, Jia, Mengping, Chen, Zhaoxiong, Gong, Wenxuan, Qin, Yue, Wang, Xinhong, Zhi, Xiuling, Lu, Meng, Chen, Sifeng, Gu, Mingxia, Zhang, Jianyi, Han, Jing-Dong J, Lan, Fei, Meng, Dan
Cyhoeddwyd yn Nucleic Acids Res (2021)

Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity

gan Sa, Silin, Gu, Mingxia, Chappell, James, Shao, Ning-Yi, Ameen, Mohamed, Elliott, Kathryn A. T., Li, Dan, Grubert, Fabian, Li, Caiyun G., Taylor, Shalina, Cao, Aiqin, Ma, Yu, Fong, Ryan, Nguyen, Long, Wu, Joseph C., Snyder, Michael P., Rabinovitch, Marlene
Cyhoeddwyd yn Am J Respir Crit Care Med (2017)

Elafin Reverses Pulmonary Hypertension via Caveolin-1–Dependent Bone Morphogenetic Protein Signaling

gan Nickel, Nils P., Spiekerkoetter, Edda, Gu, Mingxia, Li, Caiyun G., Li, Hai, Kaschwich, Mark, Diebold, Isabel, Hennigs, Jan K., Kim, Ki-Yoon, Miyagawa, Kazuya, Wang, Lingli, Cao, Aiqin, Sa, Silin, Jiang, Xinguo, Stockstill, Raymond W., Nicolls, Mark R., Zamanian, Roham T., Bland, Richard D., Rabinovitch, Marlene
Cyhoeddwyd yn Am J Respir Crit Care Med (2015)

Microfluidic Single Cell Analysis Show Porcine Induced Pluripotent Stem Cell-Derived Endothelial Cells Improve Myocardial Function by Paracrine Activation

gan Gu, Mingxia, Nguyen, Patricia K., Lee, Andrew S., Xu, Dan, Hu, Shijun, Plews, Jordan R, Han, Leng, Huber, Bruno C., Lee, Won Hee, Gong, Yongquan, de Almeida, Patricia E., Lyons, Jennifer, Ikeno, Fumi, Pacharinsak, Cholawat, Connolly, Andrew J., Gambhir, Sanjiv S., Robbins, Robert C., Longaker, Michael T., Wu, Joseph C.
Cyhoeddwyd 2012

Patient-Specific iPSC Derived Endothelial Cells Uncover Pathways that Protect Against Pulmonary Hypertension in BMPR2 Mutation Carriers

gan Gu, Mingxia, Shao, Ning-Yi, Sa, Silin, Li, Dan, Termglinchan, Vittavat, Ameen, Mohamed, Karakikes, Ioannis, Sosa, Gustavo, Grubert, Fabian, Lee, Jaecheol, Cao, Aiqin, Taylor, Shalina, Ma, Yu, Zhao, Zhixin, Chappell, James, Hamid, Rizwan, Austin, Eric D., Gold, Joseph D, Wu, Joseph C, Snyder, Michael P, Rabinovitch, Marlene
Cyhoeddwyd yn Cell Stem Cell (2016)

Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates

gan Wilson, Kitchener D., Ameen, Mohamed, Guo, Hongchao, Abilez, Oscar J., Tian, Lei, Mumbach, Maxwell R., Diecke, Sebastian, Qin, Xulei, Liu, Yonggang, Yang, Huaxiao, Ma, Ning, Gaddam, Sadhana, Cunningham, Nathan, Gu, Mingxia, Neofytou, Evgenios, Prado, Maricela, Hildebrandt, Thomas B., Karakikes, Ioannis, Chang, Howard Y., Wu, Joseph C.
Cyhoeddwyd yn Dev Cell (2020)

Patient-specific and genome-edited induced pluripotent stem cell-derived cardiomyocytes elucidate single cell phenotype of Brugada Syndrome

gan Liang, Ping, Sallam, Karim, Wu, Haodi, Li, Yingxin, Itzhaki, Ilanit, Garg, Priyanka, Zhang, Ying, Vermglinchan, Vittavat, Lan, Feng, Gu, Mingxia, Gong, Tingyu, Zhuge, Yan, He, Chunjiang, Ebert, Antje D., Sanchez-Freire, Veronica, Churko, Jared, Hu, Shijun, Sharma, Arun, Lam, Chi Keung, Scheinman, Melvin M., Bers, Donald M., Wu, Joseph C.
Cyhoeddwyd yn J Am Coll Cardiol (2016)