Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity

Rationale: Idiopathic or heritable pulmonary arterial hypertension is characterized by loss and obliteration of lung vasculature. Endothelial cell dysfunction is pivotal to the pathophysiology, but different causal mechanisms may reflect a need for patient-tailored therapies. Objectives: Endothelial...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Sa, Silin, Gu, Mingxia, Chappell, James, Shao, Ning-Yi, Ameen, Mohamed, Elliott, Kathryn A. T., Li, Dan, Grubert, Fabian, Li, Caiyun G., Taylor, Shalina, Cao, Aiqin, Ma, Yu, Fong, Ryan, Nguyen, Long, Wu, Joseph C., Snyder, Michael P., Rabinovitch, Marlene
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5387706/
https://ncbi.nlm.nih.gov/pubmed/27779452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201606-1200OC
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