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Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1 Mediated Metabolic and Epigenetic Changes

RATIONALE: Maintaining endothelial cells (EC) as a monolayer in the vessel wall depends on their metabolic state and gene expression profile, features influenced by contact with neighboring cells such as pericytes and smooth muscle cells (SMC). Failure to regenerate a normal EC monolayer in response...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Miyagawa, Kazuya, Shi, Minyi, Chen, Pin-I, Hennigs, Jan K, Zhao, Zhixin, Wang, Mouer, Li, Caiyun G, Saito, Toshie, Taylor, Shalina, Sa, Silin, Cao, Aiqin, Wang, Lingli, Snyder, Michael P, Rabinovitch, Marlene
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400637/
https://ncbi.nlm.nih.gov/pubmed/30582451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.313374
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