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BMPR2 Preserves Mitochondrial Function and DNA Integrity During Reoxygenation to Promote Endothelial Survival and Reverse Pulmonary Hypertension
Mitochondrial dysfunction, inflammation and mutant bone morphogenetic protein receptor (BMPR)2 are associated with pulmonary arterial hypertension (PAH), an incurable disease characterized by pulmonary arterial (PA) endothelial cell (EC) apoptosis, decreased microvessels and occlusive vascular remod...
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| Publicat a: | Cell Metab |
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| Autors principals: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394191/ https://ncbi.nlm.nih.gov/pubmed/25863249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.03.010 |
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