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Co-dependence of BMPR2 and TGFβ in Elastic Fiber Assembly and its Perturbation in Pulmonary Arterial Hypertension
OBJECTIVE: We determined in patients with pulmonary arterial (PA) hypertension (PAH) whether in addition to increased production of elastase by PA smooth muscle cells (SMC) previously reported, PA elastic fibers are susceptible to degradation owing to their abnormal assembly. APPROACH AND RESULTS: F...
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| Pubblicato in: | Arterioscler Thromb Vasc Biol |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5593082/ https://ncbi.nlm.nih.gov/pubmed/28619995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309696 |
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